lysyl oxidase homolog 4 (lysyl oxidase-like protein 4, lysyl oxidase-related protein C, LOXL4, LOXC)

Function

• modulates formation of collagenous extracellular matrix (putative) ,

Cofactor: Cu+, Cu+2

Structure

• belongs to the lysyl oxidase family
• contains 4 SRCR domains
• contains 1 lysine tyrosylquinone, generated by condensation of epsilon-amino group of Lys with topaquinone produced by oxidation of Tyr

Compartment

secreted

Expression

• expressed in many tissues
• highest levels in skeletal muscle, testis, pancreas
• expressed in cartilage

More general terms

• glycoprotein
• oxidoreductase
• metalloprotein
• secreted protein

Database

• OMIM: https://mirror.omim.org/entry/607318
• UniProt: http://www.uniprot.org/uniprot/Q96JB6.html