oncoprotein-induced transcript 3 protein (liver-specific zona pellucida domain-containing protein, OIT3, LZP, UNQ826/PRO1753)

Function

• may be involved in hepatocellular function & development

Structure

• contains 1 EGF-like domain
• contains 1 ZP domain

Compartment

• nuclear envelope
• can be secreted into blood

Alternative splicing

named isoforms=2

Expression

• liver-specific
• expressed only in hepatocytes

Pathology

• down-regulated in hepatocellular carcinoma (HCC) & HCC cell lines

More general terms

• nuclear protein
• glycoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8WWZ8.html