CMRF35-like molecule 9 (CLM-9, CD300 antigen-like family member G, triggering receptor expressed on myeloid cells 4, TREM-4, CD300LG, CLM9, TREM4, UNQ422/PRO846)

Function

• receptor which may mediate L-selectin-dependent lymphocyte rollings
• binds SELL in a Ca+2 dependent manner
• binds lymphocyte (putative)
• O-glycosylated with sialylated oligosaccharides

Structure

• Ig-like V-type domain mediates binding to lymphocyte
• contains 1 Ig-like V-type domain (immunoglobulin-like)

Compartment

• apical cell membrane, basolateral cell membrane
• endosome, multivesicular body

Alternative splicing

named isoforms=3

Expression

• highly expressed in heart, skeletal muscle & placenta

More general terms

• cell surface receptor
• glycoprotein
• CD300 family protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q6UXG3.html