signal peptide, CUB & EGF-like domain-containing protein 3 (SCUBE3, CEGF3)

Function

• forms homo-oligomers & hetero-oligomers with SCUBE1
• may undergo proteolytic cleavage in the C-terminal region

Structure

• N-glycosylated
• contains 1 CUB domain
• contains 9 EGF-like domains

Compartment

secreted, cell surface

Alternative splicing

named isoforms=2

Expression

• highly expressed in osteoblasts
• expression is low or absent in non-bone tissues

More general terms

• EGF-like domain-containing protein (EGFL)
• secreted protein
• glycoprotein

Additional terms

• signal peptide, CUB & EGF-like domain-containing protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8IX30.html