growth/differentiation factor 6 (GDF-6, growth/differentiation factor 16, GDF6, GDF16)

Function

• required for normal formation of bones & joints in limbs, skull, & axial skeleton
• role in establishing boundaries between skeletal elements during development

Structure

• homodimer, disulfide-linked
• belongs to the TGF-beta family

Compartment

secreted

More general terms

• secreted protein
• glycoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q6KF10.html