testis-specific protease-like protein 50 (TSP50, PRSS50)

Structure

• belongs to the peptidase S1 family
• contains 1 peptidase S1 domain
• Thr-310 is present instead of the conserved Ser which is expected to be an active site residue, thus probably not an active protease

Expression

• testis specific

Pathology

• differentially expressed in some breast cancer tissues

Genetics

• DNA hypomethylation is accompanied by the expression of the gene in the testis

More general terms

• testis-specific protein
• glycoprotein
• secreted protein

Database

• OMIM: https://mirror.omim.org/entry/607950
• UniProt: http://www.uniprot.org/uniprot/Q9UI38.html