cartilage intermediate layer protein 2 (CILP-2, CILP2)

Function

• role in cartilage scaffolding
• may be cleaved into 2 chains possibly by a furin-like protease upon or preceding secretion

Structure

• contains 1 Ig-like C2-type (immunoglobulin-like) domain.
• contains 1 TSP type-1 domain

Compartment

secreted, extracellular matrix

Expression

• expressed in articular chondrocytes
• not expressed in knee meniscal cartilage cells

More general terms

• secreted protein
• glycoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8IUL8.html