solute carrier family 13 member 3; Na+/dicarboxylate cotransporter 3; NaDC-3; hNaDC3; Na+-dependent high-affinity dicarboxylate transporter 2 (SLC13A3, NADC3, SDCT2)

Function

• high-affinity Na+-dicarboxylate cotransporter
• accepts a range of substrates with 4-5 carbon atoms
• stoichiometry is probably 3 Na+ for 1 divalent succinate

Structure

• belongs to the SLC13A transporter (TC 2.A.47) family NADC subfamily

Compartment

• cell membrane; multi-pass membrane protein

Alternative splicing

named isoforms=4

Expression

• expression is highest in kidney
• detected in placenta, brain, liver & pancreas

More general terms

• transmembrane 11 protein
• glycoprotein
• solute carrier family 13 (SLC13, SLC13A)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=64849
• OMIM: https://mirror.omim.org/entry/606411
• UniProt: http://www.uniprot.org/uniprot/Q8WWT9.html