brain-specific angiogenesis inhibitor 3

Function

• might be involved in angiogenesis inhibition & suppression of glioblastoma

Structure

• belongs to the G-protein coupled receptor 2 family LN-TM7 subfamily
• contains 1 CUB domain
• contains 1 GPS domain
• contains 4 TSP type-1 domains

Compartment

• cell membrane; multi-pass membrane protein

Expression

• strongly expressed in brain
• also detected in heart
• diminished expression in some glioblastoma cell lines

More general terms

• brain-specific angiogenesis inhibitor
• phosphoprotein

Additional terms

• angiogenesis (neovascularization, NV)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=577
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:577
• OMIM: https://mirror.omim.org/entry/602684
• UniProt: http://www.uniprot.org/uniprot/O60242.html