Lysophosphatidic acid receptor 3; LPA receptor 3; LPA-3; Lysophosphatidic acid receptor Edg-7 (LPAR3, EDG7, LPA3)

Function

• receptor for lysophosphatidic acid (LPA)
• coupled to the Gi proteins, Go proteins & Gq proteins

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane; multi-pass membrane protein

Expression

• expressed in prostate, testes, pancreas, & heart > lung & ovary
• no detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes

Pathology

• may play a role in development of ovarian cancer

More general terms

• lysophosphatidic acid receptor (LPA-R)
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2356
• OMIM: https://mirror.omim.org/entry/605106
• UniProt: http://www.uniprot.org/uniprot/Q9UBY5.html