solute carrier family 38 member 3; Na+ coupled neutral amino acid transporter 3; system N amino acid transporter 1; N-system amino acid transporter 1 (SLC38A3, G17, NAT1, SN1, SNAT3)

Function

• Na+ dependent amino acid/proton antiporter
• mediates electrogenic cotransport of glutamine & Na+ in exchange for H+
• also recognizes histidine, asparagine & alanine
• may mediate amino acid transport in either direction under physiological conditions
• may play role in nitrogen metabolism & synaptic transmission

Structure

• belongs to the amino acid/polyamine transporter 2 family

Compartment

cell membrane

More general terms

• transmembrane 10e protein
• solute carrier family 38 (SLC38, SLC38A)
• phosphoprotein
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1099
• OMIM: https://mirror.omim.org/entry/604437
• UniProt: http://www.uniprot.org/uniprot/Q99624.html