solute carrier family 35 member D1 (SLC35D1, UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter, UDP-GlcA/UDP-GalNAc transporter, UDP-galactose transporter-related protein 7, UGTrel7, KIAA0260)

Function

• transports both UDP-glucuronic acid (UDP-GlcA) & UDP-N-acetylgalactosamine (UDP-galNAc) from the cytoplasm into the endoplasmic reticulum lumen
• role in glucuronidation &/or chondroitin sulfate biosynthesis (putative)

Structure

• belongs to the TPT transporter family, SLC35D subfamily

Compartment

endoplasmic reticulum membrane

Expression

ubiquitous

Pathology

• defects in SLC35D1 are a cause of Schneckenbecken dysplasia

More general terms

• solute carrier family 35
• transmembrane 8 protein
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2316
• OMIM: https://mirror.omim.org/entry/269250
• OMIM: https://mirror.omim.org/entry/610804
• UniProt: http://www.uniprot.org/uniprot/Q9NTN3.html