solute carrier family 7 member 3 (SLC7A3, cationic amino acid transporter 3, CAT-3, cationic amino acid transporter y+, ATRC)

Function

• Na+ independent transport of the cationic amino acids arginine, lysine & ornithine

Structure

• N-glycosylated
• belongs to the amino acid-polyamine-organocation (APC) superfamily, cationic amino acid transporter (CAT) (TC 2.A.3.3) family

Compartment

cell membrane

Expression

• expressed in thymus, uterus & testis > brain, mammary gland, prostate, salivary gland & fetal spleen
• in brain, highest expression in thalamus, hippocampus & amygdala

More general terms

• solute carrier family 7 (SLC7, SLC7A)
• transmembrane 14 protein
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8488
• OMIM: https://mirror.omim.org/entry/300443
• UniProt: http://www.uniprot.org/uniprot/Q8WY07.html