solute carrier family 39 member 6; Zn+2 transporter ZIP6; Zrt- & Irt-like protein 6; ZIP-6; estrogen-regulated protein LIV-1 (SLC39A6, LIV1, ZIP6)

Function

Zn+2-influx transporter

Structure

• N-glycosylated
• belongs to the ZIP transporter (TC 2.A.5) family

Compartment

plasma membrane

Alternative splicing

named isoforms=2

Expression

• highly expressed in the breast, prostate, placenta, kidney, pituitary & corpus callosum
• weakly expressed in heart & intestine

Pathology

• highly expressed in cells derived from an adenocarcinoma of the cervix & lung carcinoma
• up-regulated by estrogen in breast cancer cells lines

More general terms

• solute carrier family 39 (SLC39, SLC39A)
• transmembrane 6e protein
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2580
• OMIM: https://mirror.omim.org/entry/608731
• UniProt: http://www.uniprot.org/uniprot/Q13433.html