T-cell surface glycoprotein CD3 delta chain; T-cell receptor T3 delta chain; CD3d (CD3D, T3D)
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Function
- component of the CD3 complex
Structure
contains 1 ITAM domain
Compartment
membrane
Pathology
- defects in CD3D are a cause of severe combined immunodeficiency disease SCIDBNK type
More general terms
- protein subunit
- plasma membrane protein
- glycoprotein
- phosphoprotein
- immunoglobulin superfamily protein
Component of
References
- ↑ UniProt http://www.uniprot.org/uniprot/P04234.html
- ↑ CD3Dbase; Note: CD3D mutation db http://bioinf.uta.fi/CD3Dbase/
- ↑ GeneReviews https://www.genecards.org/cgi-bin/carddisp.pl?gene=CD3D
- ↑ Altman A, Coggeshall KM, Mustelin T. Molecular events mediating T cell activation. Adv Immunol. 1990;48:227-360. Review. No abstract available. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1693465