interleukin-17 receptor E (IL-17 receptor E, IL-17RE, IL17RE)

Function

• receptor which can activate the MAPK signaling pathway
• seems to function at or upstream of Ras
• isoform 2 & isoform 4 may be either cytoplasmic inactive or dominant active forms
• isoform 3 & isoform 5 may act as soluble decoy receptors

Compartment

• isoform 1: membrane
• isoform 2: cytoplasm
• isoform 3: secreted
• isoform 4: cytoplasm
• isoform 5: secreted

Alternative splicing

named isoforms=5

Expression

expressed in selected tumor cell lines

More general terms

• interleukin-17 receptor (IL17R)
• glycoprotein

Additional terms

• interleukin 17 receptor E-like (IL-17 receptor E-like, IL-17RE-like, IL17REL)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1320
• UniProt: http://www.uniprot.org/uniprot/Q8NFR9.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=132014