tweety homolog 2 (hTTY2, TTYH2 C17orf29)

Function

• probable large-conductance Ca+2-activated chloride channel
• may play a role in Ca+2 signal transduction.
• may be involved in cell proliferation & cell aggregation

Structure

belongs to the tweety family

Compartment

cell membrane; Multi-pass membrane protein

Expression

• expressed in brain & testis > heart, ovary, spleen & peripheral blood

Pathology

• up-regulated in 13 of 16 renal cell carcinoma samples examined
• up-regulated in colon carcinoma

More general terms

• tweety homolog
• phosphoprotein
• glycoprotein
• transmembrane 5 protein

Database

• OMIM: https://mirror.omim.org/entry/608855
• UniProt: http://www.uniprot.org/uniprot/Q9BSA4.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=94015