receptor-type tyrosine-protein phosphatase mu; protein-tyrosine phosphatase mu; R-PTP-mu (PTPRM, PTPRL1)

Function

• role in cell-cell adhesion through homophilic interactions
• may play a key role in signal transduction & growth control

protein tyrosine phosphate + H2O = protein tyrosine + phosphate

Structure

• belongs to the protein-tyrosine phosphatase family receptor class 2B subfamily
• contains 4 fibronectin F3 modules
• contains 1 Ig-like C2-type domain
• contains 1 MAM domain
• contains 2 tyrosine-protein phosphatase domains

Compartment

• membrane; single-pass type 1 membrane protein

More general terms

• tyrosine phosphatase, receptor type
• plasma membrane protein
• glycoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5797
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5797
• OMIM: https://mirror.omim.org/entry/176888
• UniProt: http://www.uniprot.org/uniprot/P28827.html