cytochrome b558 beta subunit (cytochrome b558 heavy chain, P22 phagocyte B-cytochrome, neutrophil cytochrome B 91 kD polypeptide, CGD91phox, gp91phox, heme binding membrane glycoprotein GP91PHOX, superoxide-generating NADPH oxidase heavy chain subunit, CYBB)

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Function

Cofactor: FAD (probable)

Structure

Compartment

membrane

Pathology

More general terms

Additional terms

Component of

References

  1. Rotrosen D, Yeung CL, Leto TL, Malech HL, Kwong CH. Cytochrome b558: the flavin-binding component of the phagocyte NADPH oxidase. Science. 1992 Jun 5;256(5062):1459-62. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1318579
  2. Segal AW, Abo A. The biochemical basis of the NADPH oxidase of phagocytes. Trends Biochem Sci. 1993 Feb;18(2):43-7. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8488557
  3. Pawson T Protein modules and signalling networks Nature 373:573 1995 PMID: https://www.ncbi.nlm.nih.gov/pubmed/7531822
  4. CYBBbase; CYBB deficiency database http://bioinf.uta.fi/CYBBbase/
  5. GeneReviews https://www.genecards.org/cgi-bin/carddisp.pl?gene=CYBB
  6. UniProt http://www.uniprot.org/uniprot/P04839.html

Database