acid phosphatase-5 (tartrate-resistant acid phosphatase, TRAP, TrATPase, ACP5)

Function

-..........-

phosphate monoester + H2O <--> an alcohol + phosphate

Cofactor: binds 2 Fe+2/Fe+3 per subunit

Pathology

• normally minor intracellular isozyme of acid phosphatase; can become dominant isozyme in Gaucher's disease, Hodgkin's disease, hairy cell leukemia

More general terms

• acid phosphatase
• metalloprotein
• glycoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/P13686.html
• OMIM: https://mirror.omim.org/entry/171640
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=54