dynein heavy chain 2, axonemal (ciliary dynein heavy chain 2, axonemal beta dynein heavy chain 2, dynein heavy chain domain-containing protein 3, DNAH2, DNAHC2, DNHD3, KIAA1503)

Function

• dynein heavy chain
• force generating protein of respiratory cilia
• involved in sperm motility
• implicated in sperm flagellar assembly (putative)

Structure

• belongs to the dynein heavy chain family
• contains 5 LRR repeats (leucine-rich repeats)
• contains 5 TPR repeats

Compartment

cell projection, cilium axoneme (putative)

Alternative splicing

named isoforms=3

Expression

• expressed primarily in trachea & testis
• also expressed in lung

More general terms

• phosphoprotein
• dynein heavy chain

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1467
• OMIM: https://mirror.omim.org/entry/603333
• UniProt: http://www.uniprot.org/uniprot/Q9P225.html