monocarboxylate transporter 10 (MCT 10, T-type amino acid transporter 1, aromatic amino acid transporter 1, solute carrier family 16 member 10, SLC16A10, MCT10, TAT1)

Function

• Na+-independent transporter
• mediates the uptake of aromatic acids
• can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells

Structure

• not N-glycosylated (putative)
• belongs to the major facilitator superfamily monocarboxylate porter (TC 2.A.1.13) family

Compartment

cell membrane, basolateral cell membrane

Expression

• strongly expressed in kidney & skeletal muscle
• expressed at lower level in placenta & heart

More general terms

• phosphoprotein
• transmembrane 12e protein
• solute carrier family 16 (SLC16, SLC16A)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1172
• OMIM: https://mirror.omim.org/entry/607550
• UniProt: http://www.uniprot.org/uniprot/Q8TF71.html