splicing factor, arginine/serine-rich 2B; pre-mRNA-splicing factor SRP46; splicing factor SRp46 (SFRS2B, SRP46, SRSF8)

Function

• Invovlved in pre-mRNA alternative splicing
• phosphorylated

Structure

• belongs to the splicing factor SR family
• contains 1 RRM (RNA recognition motif) domain

Compartment

nucleus

Alternative splicing

named isoforms=2

Expression

• strongly expressed in pancreas, spleen & prostate
• weakly expressed in lung, liver & thymus

More general terms

• splicing factor; snRNP-associated protein
• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/603269
• UniProt: http://www.uniprot.org/uniprot/Q9BRL6.html