RAS & EF-hand domain-containing protein (Ras-related protein Rab-45, RASEF, RAB45)

Function

• binds predominantly GDP, & also GTP

Structure

• homodimer
• belongs to the small GTPase superfamily. Rab family
• contains 2 EF-hand domains

Compartment

cytoplasm, perinuclear region

Alternative splicing

named isoforms=2

Expression

• down-regulated in cutaneous melanoma cells but not in breast cancer cells

More general terms

• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8IZ41.html