eukaryotic translation initiation factor 3 subunit M (eIF3m, PCI domain-containing protein 1, fetal lung protein B5, hFL-B5, EIF3M, HFLB5, PCID1, GA17, PNAS-125)

Function

• component of the eIF-3 complex, which binds to the 40S ribosome & promotes the binding of methionyl-tRNAi & mRNA
• in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2), may favor virus entry
• part of the eIF-3 complex

Structure

• belongs to the CSN7/EIF3M family. EIF3M subfamily
• contains 1 PCI domain

Expression

• broadly expressed
• induced by glucose deprivation in neuroblastoma cells

More general terms

• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q7L2H7.html