UNC45 homolog A (UNC-45A, Smooth muscle cell-associated protein 1, SMAP-1, UNC45A, SMAP1)

Function

• may act as co-chaperone for HSP90
• may be necessary for proper folding of myosi
• necessary for normal cell proliferation
• necessary for normal myotube formation & myosin accumulation during muscle cell development
• may play a role in erythropoiesis in stroma cells in spleen

Structure

contains 3 TPR repeats

Alternative splicing

named isoforms=3

Expression

• detected in peripheral blood leukocytes, bone marrow, adrenal gland, trachea, spinal cord, thyroid, lymph node & stomach

More general terms

• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9H3U1.html