alpha- & gamma-adaptin-binding protein p34 (AAGAB)

Function

• may play a role in membrane traffic (putative)
• interacts with AP1G1 & AP2A1 (putative)

Pathology

• autosomal dominant nonsense point mutation c.370C->T in AAGAB gene is the cause of punctate palmoplantar keratoderma type 1)

More general terms

• phosphoprotein

Additional terms

• alpha adaptin (adaptor-related protein complex 2, alpha subunit, clathrin adaptor complex AP2, alpha subunit)
• gamma adaptin (adaptor-related protein complex, gamma subunit)

Database

• UniProt: http://www.uniprot.org/uniprot/Q6PD74.html