anti-Vgcc antibody

Etiology

• Lambert-Eaton myasthenic syndrome
• encephalomyelitis
• cerebellar degeneration
• peripheral neuropathy
• associated malignancy
  • small cell lung carcinoma

Pathology

Neuronal antigen:

• alpha-1 subunit of presynaptic voltage-gated Ca+2 channel

More general terms

• paraneoplastic autoantibody

Additional terms

• voltage-dependent Ca+2 channel alpha-1D; Ca+2 channel L type alpha-1 polypeptide isoform 2; Cav1.3 (CACNA1D CACNL1A2, CCHL1A2, CACH3, CACN4)