G2 & S phase expressed protein 1 (B99 homolog, GTSE1)

Function

• role in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements required to enter mitosis
• overexpression delays G2/M phase progression
• phosphorylated in mitosis

Compartment

cytoplasm, associated with microtubules

Expression

• expressed in G2/M phase
• not detected in quiescent cells

More general terms

• microtubule-associated protein (MAP)
• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/607477
• UniProt: http://www.uniprot.org/uniprot/Q9NYZ3.html