protein-associating with the carboxyl-terminal domain of ezrin (ezrin-binding protein PACE-1, SCY1-like protein 3, SCYL3, PACE1)

Function

• role in regulating cell adhesion/migration complexes in migrating cells (putative)
• interacts with VIL2/Ezrin C-terminal domain
• phosphorylated

Structure

• protein kinase domain is predicted to be catalytically inactive.

myristoylation may target it Golgi compartment

contains 4 HEAT repeat contains 1 protein kinase domain

Compartment

• cytoplasm, Golgi apparatus
• colocalizes with VIL2/ezrin, actin & CD44 in lamellipodia

Alternative splicing

named isoforms=2

Expression

• ubiquitously expressed

More general terms

• myristoylated protein
• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/608192
• UniProt: http://www.uniprot.org/uniprot/Q8IZE3.html