transformer-2 protein homolog TRA2A (transformer-2 protein homolog alpha, TRA-2 alpha, TRA2A)

Function

• sequence-specific RNA-binding protein
• role in pre-mRNA splicing
• binds to A3 enhancer proteins SRp75, SRp55, SRp40 & SRp30
• phosphorylated in the RS domains

Structure

• belongs to the splicing factor SR family
• contains 1 RRM domain (RNA recognition motif)

Compartment

nucleus

Alternative splicing

named isoforms=2

More general terms

• nuclear protein
• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/602718
• UniProt: http://www.uniprot.org/uniprot/Q13595.html