neuroguidin (EIF4E-binding protein, NGDN, C14orf120)

Function

• role in translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs
• interacts with CPEB1 & EIF4E

Structure

• belongs to the SAS10 family

Compartment

• nucleus, cytoplasm., axons, dendrites & filopodia
• colocalized with EIF4E in neurites

Alternative splicing

named isoforms=2

More general terms

• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8NEJ9.html