amyloid protein-binding protein 2; amyloid beta protein-binding protein 2; APP-binding protein 2; APP-BP2; protein interacting with APP tail 1 (APPBP2, KIAA0228, PAT1)

Function

• intracellular protein transport
• translocation of APP along microtubules toward cell surface
• binds APP
• rapidly degraded by the proteasome upon overexpression of a C-terminal fragment of APP

Compartment

• nucleus, cytoplasm, associated with membranes, microtubules

More general terms

• phosphoprotein

Additional terms

• amyloid precursor protein; A4/beta amyloid precursor protein (APP)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1051
• OMIM: https://mirror.omim.org/entry/605324
• UniProt: http://www.uniprot.org/uniprot/Q92624.html