retinoblastoma-binding protein 9; RBBP-9; retinoblastoma-binding protein 10; RBBP-10; B5T overexpressed gene protein; Bog protein (RBBP9 BOG RBBP10)

Function

• may play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with Rb1 & the subsequent displacement of E2F-1

Compartment

cytoplasm, nucleus

Alternative splicing

named isoforms=2

Expression

widely expressed

Pathology

• expressed at higher levels in tumor tissues than in normal tissues

More general terms

• retinoblastoma-binding protein
• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/602908
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1074
• UniProt: http://www.uniprot.org/uniprot/O75884.html