chromodomain-helicase-DNA-binding protein 5; CHD-5; ATP-dependent helicase CHD5 (CHD5, KIAA0444)

Function

• may play a role in the development of the nervous system

ATP + H2O = ADP + phosphate

Structure

• belongs to the SNF2/RAD54 helicase family
• contains 2 chromo domains
• contains 1 helicase ATP-binding domain
• contains 1 helicase C-terminal domain
• contains 2 PHD-type Zn+2 fingers

Compartment

nucleus (putative)

Expression

• preferentially expressed in total brain, fetal brain, & cerebellum
• moderately expressed in the adrenal gland

Pathology

• may play a role in the pathogenesis of neural tumors

More general terms

• chromodomain-helicase-DNA-binding protein
• zinc finger protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=26038
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:26038
• OMIM: https://mirror.omim.org/entry/610771
• UniProt: http://www.uniprot.org/uniprot/Q8TDI0.html