coilin; p80 (COIL, CLN80)

Function

• component of the nuclear coiled bodies which are involved in the function or assembly/disassembly of nucleoplasmic snRNPs
• during mitosis, nuclear coiled bodies disassemble, coinciding with mitotic-specific phosphorylation of p80 coilin
• interacts with ANKS1B

Compartment

nucleus

Expression

found in all the cell types examined

More general terms

• nuclear protein
• phosphoprotein

Component of

• Cajal coiled body

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8161
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8161
• OMIM: https://mirror.omim.org/entry/600272
• UniProt: http://www.uniprot.org/uniprot/P38432.html