tryptophanyl tRNA synthetase (WARS)

Function

-..........-

ATP + L-tryptophan + tRNA(Trp)
             <-->
AMP + diphosphate + L-tryptophyl-tRNA(Trp)

Structure

• homodimer
• belongs to aminoacyl-tRNA synthetase-2 family
• contains 1 WHEP-TRS domain

Compartment

cytoplasm

Expression

induced by interferon gamma

More general terms

• amino acyl tRNA synthetase-1
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/P23381.html
• OMIM: https://mirror.omim.org/entry/191050