isoleucyl tRNA synthetase (isoleucine-tRNA ligase, IleRS, IRS, IARS)

Function

• component of multisynthetase complex

ATP + L-isoleucine + tRNA(Ile)
           <-->
AMP + diphosphate + L-isoleucyl-tRNA(Ile)

Structure

• belongs to aminoacyl-tRNA synthetase-1 family

Compartment

cytoplasm

Notes

uncertain whether Met-1 or Met-5 is the initiator

More general terms

• amino acyl tRNA synthetase-1
• phosphoprotein

Component of

• multisynthetase complex

Database

• UniProt: http://www.uniprot.org/uniprot/P41252.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3376
• OMIM: https://mirror.omim.org/entry/600709