adenosine monophosphate deaminase-2 (AMP deaminase isoform L, AMPD2)
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Function
- AMP deaminase plays a critical role in energy metabolism
- catalyzes the hydrolytic deamination of AMP into IMP
- purine nucleotide cycle
AMP + H2O <--> IMP + NH3
Structure
- homotetramer
- belongs to the adenosine & AMP deaminases family
Alternative splicing
named isoforms=4
Expression
- predominates in smooth muscle, non-muscle tissue, embryonic muscle & undifferentiated myoblasts
More general terms
References
- ↑ Morisaki T et al Adenylate deaminase. A multigene family in humans and rats. J Biol Chem 1990 Jul 15;265(20):11482-6 PMID: https://www.ncbi.nlm.nih.gov/pubmed/2365682
- ↑ UniProt http://www.uniprot.org/uniprot/Q01433.html