anaphase promoting complex subunit 8 (cell division cycle protein 23 homolog, CDC23, APC8, cyclosome subunit 8)

Function

• component of the anaphase promoting complex/cyclosome (APC/C)
• phosphorylation on Thr-556 occurs specifically during mitosis

Structure

• belongs to the APC8/CDC23 family
• contains 9 TPR repeats

Alternative splicing

named isoforms=2

More general terms

• protein subunit
• phosphoprotein

Component of

• anaphase promoting complex (APC, cyclosome)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8697
• OMIM: https://mirror.omim.org/entry/603462
• UniProt: http://www.uniprot.org/uniprot/Q9UJX2.html