GrpE protein homolog 2, mitochondrial (Mt-GrpE#2, GRPEL2)

Function

• component of the PAM complex, alternate with GRPEL1
• regulates nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins
• stimulates ATPase activity of mt-HSP70
• modulates interconversion of oligomeric (inactive) & monomeric (active) forms of mt-HSP70

Structure

belongs to the grpE family

Compartment

mitochondrion matrix

More general terms

• mitochondrial protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8TAA5.html