glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Glu-AdT subunit B; cytochrome oxidase assembly factor PET112 homolog (PET112, PET112L, HSPC199)

Function

• allows formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria
• the reaction takes place in the presence of glutamine & ATP through an activated gamma-phospho-Glu- tRNA(Gln)
• subunit of the gatCAB amidotransferase (AdT) complex

Structure

belongs to the gatB/gatE family, gatB subfamily

Compartment

mitochondria

Expression

• predominantly expressed in tissues characterized by high rates of oxidative phosphorylation, including muscle & heart

More general terms

• protein subunit
• mitochondrial protein

Component of

• glutamyl-tRNA(Gln) amidotransferase (Glu-ADT)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5188
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5188
• OMIM: https://mirror.omim.org/entry/603645
• UniProt: http://www.uniprot.org/uniprot/O75879.html