aldehyde dehydrogenase 1 family, member B1 (aldehyde dehydrogenase 5, mitochondrial aldehyde dehydrogenase X, ALDH class 2, ALDH1B1, ALDH5, ALDHX)

Function

• along with aldehyde dehydrogenase 2, plays a major role in EtOH detoxification
• ethanol utilization, 2nd step

an aldehyde + NAD+ + H2O <--> an acid + NADH

Structure

• homotetramer (putative)
• belongs to the aldehyde dehydrogenase family

Compartment

mitochondria matrix

Expression

liver, testis & to a lesser extent in brain

More general terms

• aldehyde dehydrogenase
• mitochondrial protein

Database

• UniProt: http://www.uniprot.org/uniprot/P30837.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:219
• OMIM: https://mirror.omim.org/entry/100670
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=219