thioredoxin-2 (TRX2, mitochondrial thioredoxin, TXN2)

Function

• anti-apoptotic function
• role in the regulation of mitochondrial membrane potential
• may have role in resistance to anti-tumor agents
• dithiol-reducing activity

Structure

• belongs to the thioredoxin family
• contains 1 thioredoxin domain

Compartment

mitochondria

Expression

• widely expressed in adult (at protein level) & fetal tissues

More general terms

• thioredoxin-1 (TRX)
• mitochondrial protein

Additional terms

• thioredoxin domain-containing protein
• thioredoxin-like protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2582
• UniProt: http://www.uniprot.org/uniprot/Q99757.html