heterogeneous nuclear ribonucleoprotein A1-like protein; hnRNP core protein A1-like protein (HNRNPA1L, HNRNPA1L2)

Function

• role in the packaging of pre-mRNA into hnRNP particles
• transport of poly(A) mRNA from the nucleus to the cytoplasm
• may modulate splice site selection (putative)
• may be a component of the spliceosome C complex

Structure

contains 2 RRM (RNA recognition motif) domains

Compartment

• nucleus, cytoplasm
• shuttles continuously between the nucleus & cytoplasm along with mRNA
• component of ribonucleosomes

More general terms

• nuclear protein

Component of

• spliceosome C complex

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1449
• UniProt: http://www.uniprot.org/uniprot/Q32P51.html