polycomb group protein ASXL3 (additional sex combs-like protein 3, ASXL3, KIAA1713)

Function

• putative polycomb group protein (PcG protein)

Structure

• belongs to the Asx family
• contains 3 LRR repeats (leucine-rich repeats)
• contains 1 PHD-type Zn+2 finger

Compartment

nucleus (probable)

Alternative splicing

named isoforms=3

Expression

• expressed in pancreatic islet, testis

Pathology

• expressed in neuroblastoma, head & neck tumor

More general terms

• nuclear protein
• zinc finger protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8081
• UniProt: http://www.uniprot.org/uniprot/Q9C0F0.html