dyslexia susceptibility 1 candidate gene 1 protein (DYX1C1, EKN1)

Structure

• contains 1 CS domain contains 3 TPR repeats

Compartment

nucleus

Alternative splicing

named isoforms=2

Expression

• expressed in brain, lung, kidney, testis
• in brain localizes to a fraction of cortical neurons & white matter glial cells

Pathology

• chromosomal translocation t(2;15)(q11;q21) involving DYX1C1 may be a cause of dyslexia

More general terms

• nuclear protein

Database

• OMIM: https://mirror.omim.org/entry/127700
• OMIM: https://mirror.omim.org/entry/608706
• UniProt: http://www.uniprot.org/uniprot/Q8WXU2.html