4 1/2 half LIM domains protein 5 (FHL-5, activator of cAMP-responsive element modulator in testis, activator of CREM in testis)

Function

• regulation of spermatogenesis
• stimulates CREM transcriptional activity (phosphorylation- independent)
• interacts with CREM via the 3rd LIM domain

Structure

• contains 4 LIM zinc-binding domains

Compartment

nuclei of round & elongated spermatids

Expression

testis-specific

More general terms

• nuclear protein
• testis-specific protein

Database

• OMIM: https://mirror.omim.org/entry/605126
• UniProt: http://www.uniprot.org/uniprot/Q5TD97.html