histone-lysine N-methyltransferase H3 lysine-4 specific SET1; Set1/Ash2 histone methyltransferase complex subunit SET1; SET-domain-containing protein 1A (SETD1A, KIAA0339, SET1)

Function

• methylates Lys-4 of histone H3
• methylation specific for when part of HMT complex is methylated, except when Lys-9 residue already methylated
• component of Set1/Ash2 histone methyltransferase complex (HMT complex)

Compartment

nucleus

More general terms

• histone N-methyltransferase
• SET domain-containing protein

Component of

• Set1/Ash2 histone methyltransferase (HMT) complex

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9739
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9739
• OMIM: https://mirror.omim.org/entry/611052
• UniProt: http://www.uniprot.org/uniprot/O15047.html