ribosomal RNA methyltransferase 2; protein ftsJ homolog 2; rRNA (uridine-2'-O-)-methyltransferase-2 (FTSJ2, FJH1)

Function

• probable methyltransferase

S-adenosyl-L-methionine + rRNA = S-adenosyl-L- homocysteine + rRNA containing 2'-O-methyluridine

Structure

• belongs to the methyltransferase superfamily, RlmE family

Compartment

nucleus, nucleolus

Expression

• widely expressed, with highest expression in muscle, placenta, & heart

More general terms

• methyltransferase
• nuclear protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=29960
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:29960
• OMIM: https://mirror.omim.org/entry/606906
• UniProt: http://www.uniprot.org/uniprot/Q9UI43.html